Sayreville is located in eastern Middlesex County along the Raritan River and the western edge of Raritan Bay. The borough has a long industrial history tied to clay mining, brickmaking, chemical manufacturing, and waterfront transportation. Today it includes established residential neighborhoods, industrial and warehouse districts, retail corridors, schools, parks, and redevelopment areas. Routes 9 and 35 cross the borough, while Route 18, the Garden State Parkway, and the New Jersey Turnpike are accessible nearby. The Driscoll Bridge connects the area with Woodbridge and points north across the Raritan River. Sayreville contains several distinct local sections rather than one uniform downtown, and its shoreline continues to influence development patterns. The borough borders South Amboy, Old Bridge, East Brunswick, South River, and neighboring communities across the river.